Circulating Biomarkers of One-Carbon Metabolism in Relation to Renal Cell Carcinoma Incidence and Survival
Identifieur interne : 004256 ( Main/Exploration ); précédent : 004255; suivant : 004257Circulating Biomarkers of One-Carbon Metabolism in Relation to Renal Cell Carcinoma Incidence and Survival
Auteurs : Mattias Johansson [France] ; Anouar Fanidi [France] ; David C. Muller [France] ; Julie K. Bassett [Australie] ; Ivind Midttun [Norvège] ; Stein Emil Vollset [Norvège] ; Ruth C. Travis [Royaume-Uni] ; Domenico Palli [Italie] ; Amalia Mattiello [Italie] ; Sabina Sieri [Italie] ; Antonia Trichopoulou [Grèce] ; Pagona Lagiou [Grèce, États-Unis] ; Dimitrios Trichopoulos [Grèce, États-Unis] ; Börje Ljungberg [Suède] ; Göran Hallmans [Suède, Norvège] ; Elisabete Weiderpass [Norvège, Suède, Finlande, Espagne] ; Guri Skeie [Norvège] ; Carlos A. Gonzalez [Espagne] ; Miren Dorronsoro [Pays-Bas] ; Petra H. Peeters [Pays-Bas] ; H. B. Buenode-Mesquita [Pays-Bas, France] ; Martine M. Ros [Pays-Bas, France] ; Marie-Christine Boutron Ruault ; Guy Fagherazzi ; Françoise Clavel ; María-José Sanchez ; Aurelio Barricarte Gurrea ; Carmen Navarro ; J. Ramon Quiros ; Kim Overvad ; Anne Tj Nneland ; Krassimira Aleksandrova ; Paolo Vineis ; Marc J. Gunter ; Rudolf Kaaks ; Graham Giles [Australie] ; Caroline Relton ; Elio Riboli ; Heiner Boeing ; Per Magne Uelandt ; Gianluca Severit [Australie] ; Paul Brennant [France]Source :
- Journal of the National Cancer Institute [ 0027-8874 ] ; 2014.
Descripteurs français
- KwdFr :
- Acide folique (sang), Adulte, Adulte d'âge moyen, Carbone (métabolisme), Estimation de Kaplan-Meier, Europe (épidémiologie), Femelle, Humains, Marqueurs biologiques (sang), Modèles de hasards proportionnels, Modèles logistiques, Mâle, Néphrocarcinome (mortalité), Néphrocarcinome (sang), Néphrocarcinome (épidémiologie), Odds ratio, Riboflavine (sang), Sujet âgé, Tumeurs du rein (mortalité), Tumeurs du rein (sang), Tumeurs du rein (épidémiologie), Vitamine B12 (sang), Vitamine B6 (sang), Vitamines (sang), Études cas-témoins, Évaluation des risques.
- MESH :
- mortalité : Néphrocarcinome, Tumeurs du rein.
- métabolisme : Carbone.
- sang : Acide folique, Marqueurs biologiques, Néphrocarcinome, Riboflavine, Tumeurs du rein, Vitamine B12, Vitamine B6, Vitamines.
- épidémiologie : Europe, Néphrocarcinome, Tumeurs du rein.
- Pascal (Inist)
- Adulte, Adulte d'âge moyen, Estimation de Kaplan-Meier, Femelle, Humains, Hypernéphrome, Marqueur biologique, Carbone, Cancer rein, Modèles de hasards proportionnels, Modèles logistiques, Mâle, Métabolisme, Incidence, Epidémiologie, Odds ratio, Sujet âgé, Survie, Cancérologie, Carcinome, Études cas-témoins, Évaluation des risques.
- Wicri :
- topic : Carbone.
English descriptors
- KwdEn :
- Adult, Aged, Biological marker, Biomarkers (blood), Cancerology, Carbon, Carbon (metabolism), Carcinoma, Carcinoma, Renal Cell (blood), Carcinoma, Renal Cell (epidemiology), Carcinoma, Renal Cell (mortality), Case-Control Studies, Epidemiology, Europe (epidemiology), Female, Folic Acid (blood), Grawitz tumor, Humans, Incidence, Kaplan-Meier Estimate, Kidney Neoplasms (blood), Kidney Neoplasms (epidemiology), Kidney Neoplasms (mortality), Kidney cancer, Logistic Models, Male, Metabolism, Middle Aged, Odds Ratio, Proportional Hazards Models, Riboflavin (blood), Risk Assessment, Survival, Vitamin B 12 (blood), Vitamin B 6 (blood), Vitamins (blood).
- MESH :
- chemical , blood : Biomarkers, Folic Acid, Riboflavin, Vitamin B 12, Vitamin B 6, Vitamins.
- chemical , metabolism : Carbon.
- geographic , epidemiology : Europe.
- blood : Carcinoma, Renal Cell, Kidney Neoplasms.
- epidemiology : Carcinoma, Renal Cell, Kidney Neoplasms.
- mortality : Carcinoma, Renal Cell, Kidney Neoplasms.
- Adult, Aged, Case-Control Studies, Female, Humans, Kaplan-Meier Estimate, Logistic Models, Male, Middle Aged, Odds Ratio, Proportional Hazards Models, Risk Assessment.
Abstract
Background The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival. Methods The European Prospective Investigation into Cancer and Nutrition (EPIC) recruited 385747 participants with blood samples between 1992 and 2000, and this analysis included 556 RCC case-control pairs. A subsequent replication study included 144 case-control pairs nested within the Melbourne Collaborative Cohort Study (MCCS).
Url:
Affiliations:
- Australie, Espagne, Finlande, France, Grèce, Italie, Norvège, Pays-Bas, Royaume-Uni, Suède, États-Unis
- Angleterre, Attique (région), Auvergne-Rhône-Alpes, Catalogne, Oxfordshire, Rhône-Alpes, Svealand, Utrecht (province), Victoria (État), Østlandet
- Athènes, Barcelone, Lyon, Melbourne, Oslo, Oxford, Stockholm, Utrecht
- Université d'Oxford
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Le document en format XML
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Foundation</s1><s2>Athens</s2><s3>GRC</s3><sZ>11 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>World Health Organization Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School</s1><s2>Athens</s2><s3>GRC</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>World Health Organization Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School</s1><s2>Athens</s2><s3>GRC</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Department of Epidemiology, Harvard School of Public Health</s1><s2>Boston, MA</s2><s3>USA</s3><sZ>12 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Boston, MA</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Bureau of Epidemiologic Research, Academy of Athens</s1><s2>Athens</s2><s3>GRC</s3><sZ>12 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Trichopoulos, Dimitrios" 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type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Ljungberg, Borje" sort="Ljungberg, Borje" uniqKey="Ljungberg B" first="Börje" last="Ljungberg">Börje Ljungberg</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University</s1><s2>Umeå</s2><s3>SWE</s3><sZ>14 aut.</sZ></inist:fA14><country>Suède</country><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Hallmans, Goran" sort="Hallmans, Goran" uniqKey="Hallmans G" first="Göran" last="Hallmans">Göran Hallmans</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Department of Biobank Research, Umeå University</s1><s2>Umeå</s2><s3>SWE</s3><sZ>15 aut.</sZ></inist:fA14><country>Suède</country><wicri:noRegion>Umeå</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø</s1><s2>Tromsø</s2><s3>NOR</s3><sZ>15 aut.</sZ></inist:fA14><country>Norvège</country><wicri:noRegion>Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Department of Research, Cancer Registry of Norway</s1><s2>Oslo</s2><s3>NOR</s3><sZ>16 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Norvège</country><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="17"><s1>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>16 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Samfundet Folkhälsan</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>16 aut.</sZ></inist:fA14><country>Finlande</country><wicri:noRegion>Samfundet Folkhälsan</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="19"><s1>Catalan Institute of Oncology (ICO)</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>16 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="20"><s1>Public Health Direction, Basque regional Health Department</s1><s2>San Sebastian</s2><s3>ESP</s3><sZ>16 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>San Sebastian</wicri:noRegion></affiliation></author><author><name sortKey="Skeie, Guri" sort="Skeie, Guri" uniqKey="Skeie G" first="Guri" last="Skeie">Guri Skeie</name><affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Department of Research, Cancer Registry of Norway</s1><s2>Oslo</s2><s3>NOR</s3><sZ>16 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Norvège</country><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Gonzalez, Carlos A" sort="Gonzalez, Carlos A" uniqKey="Gonzalez C" first="Carlos A." last="Gonzalez">Carlos A. Gonzalez</name><affiliation wicri:level="1"><inist:fA14 i1="21"><s1>Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP) - Health Research Institute (BIODONOSTIA)</s1><s3>ESP</s3><sZ>18 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP) - Health Research Institute (BIODONOSTIA)</wicri:noRegion></affiliation></author><author><name sortKey="Dorronsoro, Miren" sort="Dorronsoro, Miren" uniqKey="Dorronsoro M" first="Miren" last="Dorronsoro">Miren Dorronsoro</name><affiliation wicri:level="3"><inist:fA14 i1="22"><s1>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>19 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Peeters, Petra H" sort="Peeters, Petra H" uniqKey="Peeters P" first="Petra H." last="Peeters">Petra H. Peeters</name><affiliation wicri:level="3"><inist:fA14 i1="24"><s1>Department of Gastroenterology and Hepatology, University Medical Centre</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>20 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Buenode Mesquita, H B" sort="Buenode Mesquita, H B" uniqKey="Buenode Mesquita H" first="H. B." last="Buenode-Mesquita">H. B. Buenode-Mesquita</name><affiliation wicri:level="1"><inist:fA14 i1="23"><s1>National Institute for Public Health and the Environment (RIVM)</s1><s2>Bilthoven</s2><s3>NLD</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>Pays-Bas</country><wicri:noRegion>National Institute for Public Health and the Environment (RIVM)</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="25"><s1>Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health team</s1><s2>Villejuif</s2><s3>FRA</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Hormones and Women's Health team</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Ros, Martine M" sort="Ros, Martine M" uniqKey="Ros M" first="Martine M." last="Ros">Martine M. Ros</name><affiliation wicri:level="1"><inist:fA14 i1="23"><s1>National Institute for Public Health and the Environment (RIVM)</s1><s2>Bilthoven</s2><s3>NLD</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>Pays-Bas</country><wicri:noRegion>National Institute for Public Health and the Environment (RIVM)</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="25"><s1>Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health team</s1><s2>Villejuif</s2><s3>FRA</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Hormones and Women's Health team</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Ruault, Marie Christine Boutron" sort="Ruault, Marie Christine Boutron" uniqKey="Ruault M" first="Marie-Christine Boutron" last="Ruault">Marie-Christine Boutron Ruault</name></author><author><name sortKey="Fagherazzi, Guy" sort="Fagherazzi, Guy" uniqKey="Fagherazzi G" first="Guy" last="Fagherazzi">Guy Fagherazzi</name></author><author><name sortKey="Clavel, Francoise" sort="Clavel, Francoise" uniqKey="Clavel F" first="Françoise" last="Clavel">Françoise Clavel</name></author><author><name sortKey="Sanchez, Maria Jose" sort="Sanchez, Maria Jose" uniqKey="Sanchez M" first="María-José" last="Sanchez">María-José Sanchez</name></author><author><name sortKey="Gurrea, Aurelio Barricarte" sort="Gurrea, Aurelio Barricarte" uniqKey="Gurrea A" first="Aurelio Barricarte" last="Gurrea">Aurelio Barricarte Gurrea</name></author><author><name sortKey="Navarro, Carmen" sort="Navarro, Carmen" uniqKey="Navarro C" first="Carmen" last="Navarro">Carmen Navarro</name></author><author><name sortKey="Quiros, J Ramon" sort="Quiros, J Ramon" uniqKey="Quiros J" first="J. Ramon" last="Quiros">J. Ramon Quiros</name></author><author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name></author><author><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name></author><author><name sortKey="Aleksandrova, Krassimira" sort="Aleksandrova, Krassimira" uniqKey="Aleksandrova K" first="Krassimira" last="Aleksandrova">Krassimira Aleksandrova</name></author><author><name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name></author><author><name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J." last="Gunter">Marc J. Gunter</name></author><author><name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name></author><author><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Cancer Epidemiology Centre, The Cancer Council Victoria</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>4 aut.</sZ><sZ>36 aut.</sZ><sZ>41 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Relton, Caroline" sort="Relton, Caroline" uniqKey="Relton C" first="Caroline" last="Relton">Caroline Relton</name></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name></author><author><name sortKey="Uelandt, Per Magne" sort="Uelandt, Per Magne" uniqKey="Uelandt P" first="Per Magne" last="Uelandt">Per Magne Uelandt</name></author><author><name sortKey="Severit, Gianluca" sort="Severit, Gianluca" uniqKey="Severit G" first="Gianluca" last="Severit">Gianluca Severit</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Cancer Epidemiology Centre, The Cancer Council Victoria</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>4 aut.</sZ><sZ>36 aut.</sZ><sZ>41 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Brennant, Paul" sort="Brennant, Paul" uniqKey="Brennant P" first="Paul" last="Brennant">Paul Brennant</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>International Agency for Research on Cancer</s1><s2>Lyon</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>42 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">15-0030911</idno><date when="2014">2014</date><idno type="stanalyst">PASCAL 15-0030911 INIST</idno><idno type="RBID">Pascal:15-0030911</idno><idno type="wicri:Area/PascalFrancis/Corpus">000049</idno><idno type="wicri:Area/PascalFrancis/Curation">005E04</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000403</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000403</idno><idno type="wicri:doubleKey">0027-8874:2014:Johansson M:circulating:biomarkers:of</idno><idno type="wicri:Area/Main/Merge">004327</idno><idno type="wicri:source">PMC</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273895</idno><idno type="RBID">PMC:4273895</idno><idno type="wicri:Area/Pmc/Corpus">002701</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002701</idno><idno type="wicri:Area/Pmc/Curation">002551</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002551</idno><idno type="wicri:Area/Pmc/Checkpoint">001711</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001711</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">003333</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003333</idno><idno type="wicri:Area/PubMed/Curation">003222</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003222</idno><idno type="wicri:Area/PubMed/Checkpoint">003222</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">003222</idno><idno type="wicri:Area/Ncbi/Merge">001F64</idno><idno type="wicri:Area/Ncbi/Curation">001F64</idno><idno type="wicri:Area/Ncbi/Checkpoint">001F64</idno><idno type="wicri:doubleKey">0027-8874:2014:Johansson M:circulating:biomarkers:of</idno><idno type="wicri:Area/Main/Merge">003B87</idno><idno type="wicri:Area/Main/Curation">004256</idno><idno type="wicri:Area/Main/Exploration">004256</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Circulating Biomarkers of One-Carbon Metabolism in Relation to Renal Cell Carcinoma Incidence and Survival</title><author><name sortKey="Johansson, Mattias" sort="Johansson, Mattias" uniqKey="Johansson M" first="Mattias" last="Johansson">Mattias Johansson</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>International Agency for Research on Cancer</s1><s2>Lyon</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>42 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Fanidi, Anouar" sort="Fanidi, Anouar" uniqKey="Fanidi A" first="Anouar" last="Fanidi">Anouar Fanidi</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>International Agency for Research on Cancer</s1><s2>Lyon</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>42 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Muller, David C" sort="Muller, David C" uniqKey="Muller D" first="David C." last="Muller">David C. Muller</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>International Agency for Research on Cancer</s1><s2>Lyon</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>42 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Bassett, Julie K" sort="Bassett, Julie K" uniqKey="Bassett J" first="Julie K." last="Bassett">Julie K. Bassett</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Cancer Epidemiology Centre, The Cancer Council Victoria</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>4 aut.</sZ><sZ>36 aut.</sZ><sZ>41 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Midttun, Ivind" sort="Midttun, Ivind" uniqKey="Midttun " first=" Ivind" last="Midttun"> Ivind Midttun</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Bevital AS</s1><s2>Bergen</s2><s3>NOR</s3><sZ>5 aut.</sZ></inist:fA14><country>Norvège</country><wicri:noRegion>Bevital AS</wicri:noRegion></affiliation></author><author><name sortKey="Vollset, Stein Emil" sort="Vollset, Stein Emil" uniqKey="Vollset S" first="Stein Emil" last="Vollset">Stein Emil Vollset</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Norwegian Institute of Public Health and Department of Global Public Health and Primary Care, University of Bergen</s1><s2>Bergen</s2><s3>NOR</s3><sZ>6 aut.</sZ></inist:fA14><country>Norvège</country><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C." last="Travis">Ruth C. Travis</name><affiliation wicri:level="4"><inist:fA14 i1="05"><s1>Nuffield Department of Clinical Medicine, University of Oxford</s1><s2>Oxford</s2><s3>GBR</s3><sZ>7 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Palli, Domenico" sort="Palli, Domenico" uniqKey="Palli D" first="Domenico" last="Palli">Domenico Palli</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO)</s1><s2>Florence</s2><s3>ITA</s3><sZ>8 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Mattiello, Amalia" sort="Mattiello, Amalia" uniqKey="Mattiello A" first="Amalia" last="Mattiello">Amalia Mattiello</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Dipartimento di Medicina Clinica e Chirurgia, Federico II University</s1><s2>Naples</s2><s3>ITA</s3><sZ>9 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Sieri, Sabina" sort="Sieri, Sabina" uniqKey="Sieri S" first="Sabina" last="Sieri">Sabina Sieri</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori</s1><s2>Milano</s2><s3>ITA</s3><sZ>10 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name><affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Hellenic Health Foundation</s1><s2>Athens</s2><s3>GRC</s3><sZ>11 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>World Health Organization Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School</s1><s2>Athens</s2><s3>GRC</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>World Health Organization Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School</s1><s2>Athens</s2><s3>GRC</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Department of Epidemiology, Harvard School of Public Health</s1><s2>Boston, MA</s2><s3>USA</s3><sZ>12 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Boston, MA</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Bureau of Epidemiologic Research, Academy of Athens</s1><s2>Athens</s2><s3>GRC</s3><sZ>12 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Hellenic Health Foundation</s1><s2>Athens</s2><s3>GRC</s3><sZ>11 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Department of Epidemiology, Harvard School of Public Health</s1><s2>Boston, MA</s2><s3>USA</s3><sZ>12 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Boston, MA</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Bureau of Epidemiologic Research, Academy of Athens</s1><s2>Athens</s2><s3>GRC</s3><sZ>12 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>Grèce</country><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Ljungberg, Borje" sort="Ljungberg, Borje" uniqKey="Ljungberg B" first="Börje" last="Ljungberg">Börje Ljungberg</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University</s1><s2>Umeå</s2><s3>SWE</s3><sZ>14 aut.</sZ></inist:fA14><country>Suède</country><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Hallmans, Goran" sort="Hallmans, Goran" uniqKey="Hallmans G" first="Göran" last="Hallmans">Göran Hallmans</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Department of Biobank Research, Umeå University</s1><s2>Umeå</s2><s3>SWE</s3><sZ>15 aut.</sZ></inist:fA14><country>Suède</country><wicri:noRegion>Umeå</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø</s1><s2>Tromsø</s2><s3>NOR</s3><sZ>15 aut.</sZ></inist:fA14><country>Norvège</country><wicri:noRegion>Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Department of Research, Cancer Registry of Norway</s1><s2>Oslo</s2><s3>NOR</s3><sZ>16 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Norvège</country><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="17"><s1>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>16 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Samfundet Folkhälsan</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>16 aut.</sZ></inist:fA14><country>Finlande</country><wicri:noRegion>Samfundet Folkhälsan</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="19"><s1>Catalan Institute of Oncology (ICO)</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>16 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="20"><s1>Public Health Direction, Basque regional Health Department</s1><s2>San Sebastian</s2><s3>ESP</s3><sZ>16 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>San Sebastian</wicri:noRegion></affiliation></author><author><name sortKey="Skeie, Guri" sort="Skeie, Guri" uniqKey="Skeie G" first="Guri" last="Skeie">Guri Skeie</name><affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Department of Research, Cancer Registry of Norway</s1><s2>Oslo</s2><s3>NOR</s3><sZ>16 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Norvège</country><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Gonzalez, Carlos A" sort="Gonzalez, Carlos A" uniqKey="Gonzalez C" first="Carlos A." last="Gonzalez">Carlos A. Gonzalez</name><affiliation wicri:level="1"><inist:fA14 i1="21"><s1>Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP) - Health Research Institute (BIODONOSTIA)</s1><s3>ESP</s3><sZ>18 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP) - Health Research Institute (BIODONOSTIA)</wicri:noRegion></affiliation></author><author><name sortKey="Dorronsoro, Miren" sort="Dorronsoro, Miren" uniqKey="Dorronsoro M" first="Miren" last="Dorronsoro">Miren Dorronsoro</name><affiliation wicri:level="3"><inist:fA14 i1="22"><s1>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>19 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Peeters, Petra H" sort="Peeters, Petra H" uniqKey="Peeters P" first="Petra H." last="Peeters">Petra H. Peeters</name><affiliation wicri:level="3"><inist:fA14 i1="24"><s1>Department of Gastroenterology and Hepatology, University Medical Centre</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>20 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Buenode Mesquita, H B" sort="Buenode Mesquita, H B" uniqKey="Buenode Mesquita H" first="H. B." last="Buenode-Mesquita">H. B. Buenode-Mesquita</name><affiliation wicri:level="1"><inist:fA14 i1="23"><s1>National Institute for Public Health and the Environment (RIVM)</s1><s2>Bilthoven</s2><s3>NLD</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>Pays-Bas</country><wicri:noRegion>National Institute for Public Health and the Environment (RIVM)</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="25"><s1>Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health team</s1><s2>Villejuif</s2><s3>FRA</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Hormones and Women's Health team</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Ros, Martine M" sort="Ros, Martine M" uniqKey="Ros M" first="Martine M." last="Ros">Martine M. Ros</name><affiliation wicri:level="1"><inist:fA14 i1="23"><s1>National Institute for Public Health and the Environment (RIVM)</s1><s2>Bilthoven</s2><s3>NLD</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>Pays-Bas</country><wicri:noRegion>National Institute for Public Health and the Environment (RIVM)</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="25"><s1>Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health team</s1><s2>Villejuif</s2><s3>FRA</s3><sZ>21 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Hormones and Women's Health team</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Ruault, Marie Christine Boutron" sort="Ruault, Marie Christine Boutron" uniqKey="Ruault M" first="Marie-Christine Boutron" last="Ruault">Marie-Christine Boutron Ruault</name></author><author><name sortKey="Fagherazzi, Guy" sort="Fagherazzi, Guy" uniqKey="Fagherazzi G" first="Guy" last="Fagherazzi">Guy Fagherazzi</name></author><author><name sortKey="Clavel, Francoise" sort="Clavel, Francoise" uniqKey="Clavel F" first="Françoise" last="Clavel">Françoise Clavel</name></author><author><name sortKey="Sanchez, Maria Jose" sort="Sanchez, Maria Jose" uniqKey="Sanchez M" first="María-José" last="Sanchez">María-José Sanchez</name></author><author><name sortKey="Gurrea, Aurelio Barricarte" sort="Gurrea, Aurelio Barricarte" uniqKey="Gurrea A" first="Aurelio Barricarte" last="Gurrea">Aurelio Barricarte Gurrea</name></author><author><name sortKey="Navarro, Carmen" sort="Navarro, Carmen" uniqKey="Navarro C" first="Carmen" last="Navarro">Carmen Navarro</name></author><author><name sortKey="Quiros, J Ramon" sort="Quiros, J Ramon" uniqKey="Quiros J" first="J. Ramon" last="Quiros">J. Ramon Quiros</name></author><author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name></author><author><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name></author><author><name sortKey="Aleksandrova, Krassimira" sort="Aleksandrova, Krassimira" uniqKey="Aleksandrova K" first="Krassimira" last="Aleksandrova">Krassimira Aleksandrova</name></author><author><name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name></author><author><name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J." last="Gunter">Marc J. Gunter</name></author><author><name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name></author><author><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Cancer Epidemiology Centre, The Cancer Council Victoria</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>4 aut.</sZ><sZ>36 aut.</sZ><sZ>41 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Relton, Caroline" sort="Relton, Caroline" uniqKey="Relton C" first="Caroline" last="Relton">Caroline Relton</name></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name></author><author><name sortKey="Uelandt, Per Magne" sort="Uelandt, Per Magne" uniqKey="Uelandt P" first="Per Magne" last="Uelandt">Per Magne Uelandt</name></author><author><name sortKey="Severit, Gianluca" sort="Severit, Gianluca" uniqKey="Severit G" first="Gianluca" last="Severit">Gianluca Severit</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Cancer Epidemiology Centre, The Cancer Council Victoria</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>4 aut.</sZ><sZ>36 aut.</sZ><sZ>41 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Brennant, Paul" sort="Brennant, Paul" uniqKey="Brennant P" first="Paul" last="Brennant">Paul Brennant</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>International Agency for Research on Cancer</s1><s2>Lyon</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>42 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Journal of the National Cancer Institute</title><title level="j" type="abbreviated">J. Natl. Cancer Inst.</title><idno type="ISSN">0027-8874</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Journal of the National Cancer Institute</title><title level="j" type="abbreviated">J. Natl. Cancer Inst.</title><idno type="ISSN">0027-8874</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Biological marker</term><term>Biomarkers (blood)</term><term>Cancerology</term><term>Carbon</term><term>Carbon (metabolism)</term><term>Carcinoma</term><term>Carcinoma, Renal Cell (blood)</term><term>Carcinoma, Renal Cell (epidemiology)</term><term>Carcinoma, Renal Cell (mortality)</term><term>Case-Control Studies</term><term>Epidemiology</term><term>Europe (epidemiology)</term><term>Female</term><term>Folic Acid (blood)</term><term>Grawitz tumor</term><term>Humans</term><term>Incidence</term><term>Kaplan-Meier Estimate</term><term>Kidney Neoplasms (blood)</term><term>Kidney Neoplasms (epidemiology)</term><term>Kidney Neoplasms (mortality)</term><term>Kidney cancer</term><term>Logistic Models</term><term>Male</term><term>Metabolism</term><term>Middle Aged</term><term>Odds Ratio</term><term>Proportional Hazards Models</term><term>Riboflavin (blood)</term><term>Risk Assessment</term><term>Survival</term><term>Vitamin B 12 (blood)</term><term>Vitamin B 6 (blood)</term><term>Vitamins (blood)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acide folique (sang)</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Carbone (métabolisme)</term><term>Estimation de Kaplan-Meier</term><term>Europe (épidémiologie)</term><term>Femelle</term><term>Humains</term><term>Marqueurs biologiques (sang)</term><term>Modèles de hasards proportionnels</term><term>Modèles logistiques</term><term>Mâle</term><term>Néphrocarcinome (mortalité)</term><term>Néphrocarcinome (sang)</term><term>Néphrocarcinome (épidémiologie)</term><term>Odds ratio</term><term>Riboflavine (sang)</term><term>Sujet âgé</term><term>Tumeurs du rein (mortalité)</term><term>Tumeurs du rein (sang)</term><term>Tumeurs du rein (épidémiologie)</term><term>Vitamine B12 (sang)</term><term>Vitamine B6 (sang)</term><term>Vitamines (sang)</term><term>Études cas-témoins</term><term>Évaluation des risques</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Biomarkers</term><term>Folic Acid</term><term>Riboflavin</term><term>Vitamin B 12</term><term>Vitamin B 6</term><term>Vitamins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Carbon</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Europe</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Carcinoma, Renal Cell</term><term>Kidney Neoplasms</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Carcinoma, Renal Cell</term><term>Kidney Neoplasms</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Carcinoma, Renal Cell</term><term>Kidney Neoplasms</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Néphrocarcinome</term><term>Tumeurs du rein</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Carbone</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Acide folique</term><term>Marqueurs biologiques</term><term>Néphrocarcinome</term><term>Riboflavine</term><term>Tumeurs du rein</term><term>Vitamine B12</term><term>Vitamine B6</term><term>Vitamines</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Europe</term><term>Néphrocarcinome</term><term>Tumeurs du rein</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Case-Control Studies</term><term>Female</term><term>Humans</term><term>Kaplan-Meier Estimate</term><term>Logistic Models</term><term>Male</term><term>Middle Aged</term><term>Odds Ratio</term><term>Proportional Hazards Models</term><term>Risk Assessment</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Estimation de Kaplan-Meier</term><term>Femelle</term><term>Humains</term><term>Hypernéphrome</term><term>Marqueur biologique</term><term>Carbone</term><term>Cancer rein</term><term>Modèles de hasards proportionnels</term><term>Modèles logistiques</term><term>Mâle</term><term>Métabolisme</term><term>Incidence</term><term>Epidémiologie</term><term>Odds ratio</term><term>Sujet âgé</term><term>Survie</term><term>Cancérologie</term><term>Carcinome</term><term>Études cas-témoins</term><term>Évaluation des risques</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Carbone</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival. Methods The European Prospective Investigation into Cancer and Nutrition (EPIC) recruited 385747 participants with blood samples between 1992 and 2000, and this analysis included 556 RCC case-control pairs. A subsequent replication study included 144 case-control pairs nested within the Melbourne Collaborative Cohort Study (MCCS).</div></front></TEI><affiliations><list><country><li>Australie</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Grèce</li><li>Italie</li><li>Norvège</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Attique (région)</li><li>Auvergne-Rhône-Alpes</li><li>Catalogne</li><li>Oxfordshire</li><li>Rhône-Alpes</li><li>Svealand</li><li>Utrecht (province)</li><li>Victoria (État)</li><li>Østlandet</li></region><settlement><li>Athènes</li><li>Barcelone</li><li>Lyon</li><li>Melbourne</li><li>Oslo</li><li>Oxford</li><li>Stockholm</li><li>Utrecht</li></settlement><orgName><li>Université d'Oxford</li></orgName></list><tree><noCountry><name sortKey="Aleksandrova, Krassimira" sort="Aleksandrova, Krassimira" uniqKey="Aleksandrova K" first="Krassimira" last="Aleksandrova">Krassimira Aleksandrova</name><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><name sortKey="Clavel, Francoise" sort="Clavel, Francoise" uniqKey="Clavel F" first="Françoise" last="Clavel">Françoise Clavel</name><name sortKey="Fagherazzi, Guy" sort="Fagherazzi, Guy" uniqKey="Fagherazzi G" first="Guy" last="Fagherazzi">Guy Fagherazzi</name><name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J." last="Gunter">Marc J. Gunter</name><name sortKey="Gurrea, Aurelio Barricarte" sort="Gurrea, Aurelio Barricarte" uniqKey="Gurrea A" first="Aurelio Barricarte" last="Gurrea">Aurelio Barricarte Gurrea</name><name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name><name sortKey="Navarro, Carmen" sort="Navarro, Carmen" uniqKey="Navarro C" first="Carmen" last="Navarro">Carmen Navarro</name><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name><name sortKey="Quiros, J Ramon" sort="Quiros, J Ramon" uniqKey="Quiros J" first="J. Ramon" last="Quiros">J. Ramon Quiros</name><name sortKey="Relton, Caroline" sort="Relton, Caroline" uniqKey="Relton C" first="Caroline" last="Relton">Caroline Relton</name><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><name sortKey="Ruault, Marie Christine Boutron" sort="Ruault, Marie Christine Boutron" uniqKey="Ruault M" first="Marie-Christine Boutron" last="Ruault">Marie-Christine Boutron Ruault</name><name sortKey="Sanchez, Maria Jose" sort="Sanchez, Maria Jose" uniqKey="Sanchez M" first="María-José" last="Sanchez">María-José Sanchez</name><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name><name sortKey="Uelandt, Per Magne" sort="Uelandt, Per Magne" uniqKey="Uelandt P" first="Per Magne" last="Uelandt">Per Magne Uelandt</name><name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name></noCountry><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Johansson, Mattias" sort="Johansson, Mattias" uniqKey="Johansson M" first="Mattias" last="Johansson">Mattias Johansson</name></region><name sortKey="Brennant, Paul" sort="Brennant, Paul" uniqKey="Brennant P" first="Paul" last="Brennant">Paul Brennant</name><name sortKey="Buenode Mesquita, H B" sort="Buenode Mesquita, H B" uniqKey="Buenode Mesquita H" first="H. B." last="Buenode-Mesquita">H. B. Buenode-Mesquita</name><name sortKey="Fanidi, Anouar" sort="Fanidi, Anouar" uniqKey="Fanidi A" first="Anouar" last="Fanidi">Anouar Fanidi</name><name sortKey="Muller, David C" sort="Muller, David C" uniqKey="Muller D" first="David C." last="Muller">David C. Muller</name><name sortKey="Ros, Martine M" sort="Ros, Martine M" uniqKey="Ros M" first="Martine M." last="Ros">Martine M. Ros</name></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Bassett, Julie K" sort="Bassett, Julie K" uniqKey="Bassett J" first="Julie K." last="Bassett">Julie K. Bassett</name></region><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name><name sortKey="Severit, Gianluca" sort="Severit, Gianluca" uniqKey="Severit G" first="Gianluca" last="Severit">Gianluca Severit</name></country><country name="Norvège"><noRegion><name sortKey="Midttun, Ivind" sort="Midttun, Ivind" uniqKey="Midttun " first=" Ivind" last="Midttun"> Ivind Midttun</name></noRegion><name sortKey="Hallmans, Goran" sort="Hallmans, Goran" uniqKey="Hallmans G" first="Göran" last="Hallmans">Göran Hallmans</name><name sortKey="Skeie, Guri" sort="Skeie, Guri" uniqKey="Skeie G" first="Guri" last="Skeie">Guri Skeie</name><name sortKey="Vollset, Stein Emil" sort="Vollset, Stein Emil" uniqKey="Vollset S" first="Stein Emil" last="Vollset">Stein Emil Vollset</name><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C." last="Travis">Ruth C. Travis</name></region></country><country name="Italie"><noRegion><name sortKey="Palli, Domenico" sort="Palli, Domenico" uniqKey="Palli D" first="Domenico" last="Palli">Domenico Palli</name></noRegion><name sortKey="Mattiello, Amalia" sort="Mattiello, Amalia" uniqKey="Mattiello A" first="Amalia" last="Mattiello">Amalia Mattiello</name><name sortKey="Sieri, Sabina" sort="Sieri, Sabina" uniqKey="Sieri S" first="Sabina" last="Sieri">Sabina Sieri</name></country><country name="Grèce"><region name="Attique (région)"><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name></region><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name></country><country name="États-Unis"><noRegion><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name></noRegion><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name></country><country name="Suède"><noRegion><name sortKey="Ljungberg, Borje" sort="Ljungberg, Borje" uniqKey="Ljungberg B" first="Börje" last="Ljungberg">Börje Ljungberg</name></noRegion><name sortKey="Hallmans, Goran" sort="Hallmans, Goran" uniqKey="Hallmans G" first="Göran" last="Hallmans">Göran Hallmans</name><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name></country><country name="Finlande"><noRegion><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name></noRegion></country><country name="Espagne"><region name="Catalogne"><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name></region><name sortKey="Gonzalez, Carlos A" sort="Gonzalez, Carlos A" uniqKey="Gonzalez C" first="Carlos A." last="Gonzalez">Carlos A. Gonzalez</name><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name></country><country name="Pays-Bas"><region name="Utrecht (province)"><name sortKey="Dorronsoro, Miren" sort="Dorronsoro, Miren" uniqKey="Dorronsoro M" first="Miren" last="Dorronsoro">Miren Dorronsoro</name></region><name sortKey="Buenode Mesquita, H B" sort="Buenode Mesquita, H B" uniqKey="Buenode Mesquita H" first="H. B." last="Buenode-Mesquita">H. B. Buenode-Mesquita</name><name sortKey="Peeters, Petra H" sort="Peeters, Petra H" uniqKey="Peeters P" first="Petra H." last="Peeters">Petra H. Peeters</name><name sortKey="Ros, Martine M" sort="Ros, Martine M" uniqKey="Ros M" first="Martine M." last="Ros">Martine M. Ros</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Circulating Biomarkers of One-Carbon Metabolism in Relation to Renal Cell Carcinoma Incidence and Survival
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